• Target：
• CRMP-3

• Gene Name：
• DPYSL4

• Protein Name：
• Dihydropyrimidinase-related protein 4

• Human Gene Id：
• 10570

• Human Swiss Prot No：
• O14531

• Mouse Swiss Prot No：
• O35098

• Rat Gene Id：
• 25417

• Rat Swiss Prot No：
• Q62951

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140

• Specificity：
• CRMP-3 Polyclonal Antibody detects endogenous levels of CRMP-3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• DPYSL4;CRMP3;ULIP4;Dihydropyrimidinase-related protein 4;DRP-4;Collapsin response mediator protein 3;CRMP-3;UNC33-like phosphoprotein 4;ULIP-4

• Observed Band(KD)：
• 62kD

• Background：
• disease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer.,function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.,

• Function：
• disease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer.,function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Brain,Fetal brain,Retina,

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