• Target：
• Dvl-3

• Fields：
• >>mTOR signaling pathway;>>Wnt signaling pathway;>>Notch signaling pathway;>>Hippo signaling pathway;>>Signaling pathways regulating pluripotency of stem cells;>>Melanogenesis;>>Cushing syndrome;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Pathways in cancer;>>Basal cell carcinoma;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer

• Gene Name：
• DVL3

• Protein Name：
• Segment polarity protein dishevelled homolog DVL-3

• Human Gene Id：
• 1857

• Human Swiss Prot No：
• Q92997

• Mouse Gene Id：
• 13544

• Mouse Swiss Prot No：
• Q61062

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human DVL3. AA range:326-375

• Specificity：
• Dvl-3 Polyclonal Antibody detects endogenous levels of Dvl-3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• DVL3;KIAA0208;Segment polarity protein dishevelled homolog DVL-3;Dishevelled-3;DSH homolog 3

• Molecular Weight(Da)：
• 78kD

• Background：
• This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008],

• Function：
• function:May play a role in the signal transduction pathway mediated by multiple Wnt genes.,similarity:Belongs to the DSH family.,similarity:Contains 1 DEP domain.,similarity:Contains 1 DIX domain.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity). Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Bone marrow,Brain,Hippocampus,Placenta,Uterus,

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