• Target：
• GBP4

• Fields：
• >>NOD-like receptor signaling pathway

• Gene Name：
• GBP4

• Protein Name：
• Guanylate-binding protein 4

• Human Gene Id：
• 115361

• Human Swiss Prot No：
• Q96PP9

• Mouse Swiss Prot No：
• Q61107

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GBP4. AA range:551-600

• Specificity：
• GBP4 Polyclonal Antibody detects endogenous levels of GBP4 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GBP4;Guanylate-binding protein 4;GTP-binding protein 4;GBP-4;Guanine nucleotide-binding protein 4

• Observed Band(KD)：
• 73kD

• Background：
• Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008],

• Function：
• function:Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation.,similarity:Belongs to the GBP family.,

• Subcellular Location：
• Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .

• Expression：
• Brain,Epithelium,Placenta,Spinal cord,Spleen,Testis,

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