GRK 7 Polyclonal Antibody

    • Catalog No.:YT2072
    • Applications:WB;IF;ELISA
    • Reactivity:Human
      • Target:
      • GRK 7
      • Fields:
      • >>Chemokine signaling pathway;>>Endocytosis;>>Phototransduction
      • Gene Name:
      • GRK7
      • Protein Name:
      • G protein-coupled receptor kinase 7
      • Human Swiss Prot No:
      • Q8WTQ7
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GRK7. AA range:371-420
      • Specificity:
      • GRK 7 Polyclonal Antibody detects endogenous levels of GRK 7 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GRK7;GPRK7;G protein-coupled receptor kinase 7;G protein-coupled receptor kinase GRK7
      • Observed Band(KD):
      • 62kD
      • Background:
      • This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008],
      • Function:
      • catalytic activity:ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.,function:Phosphorylates cone opsins thereby initiating their deactivation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 RGS domain.,tissue specificity:Retina. Cones and rod.,
      • Subcellular Location:
      • Membrane ; Lipid-anchor .
      • Expression:
      • Retinal cones, outer and inner segments.
      • Products Images
      • Western Blot analysis of various cells using GRK 7 Polyclonal Antibody
      • Western blot analysis of lysates from COLO205, Jurkat, and HeLa cells, using GRK7 Antibody. The lane on the right is blocked with the synthesized peptide.