GRK 7 Polyclonal Antibody
- Catalog No.:YT2072
- Applications:WB;IF;ELISA
- Reactivity:Human
- Target:
- GRK 7
- Fields:
- >>Chemokine signaling pathway;>>Endocytosis;>>Phototransduction
- Gene Name:
- GRK7
- Protein Name:
- G protein-coupled receptor kinase 7
- Human Gene Id:
- 131890
- Human Swiss Prot No:
- Q8WTQ7
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GRK7. AA range:371-420
- Specificity:
- GRK 7 Polyclonal Antibody detects endogenous levels of GRK 7 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- GRK7;GPRK7;G protein-coupled receptor kinase 7;G protein-coupled receptor kinase GRK7
- Observed Band(KD):
- 62kD
- Background:
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008],
- Function:
- catalytic activity:ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.,function:Phosphorylates cone opsins thereby initiating their deactivation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 RGS domain.,tissue specificity:Retina. Cones and rod.,
- Subcellular Location:
- Membrane ; Lipid-anchor .
- Expression:
- Retinal cones, outer and inner segments.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using GRK 7 Polyclonal Antibody
- Western blot analysis of lysates from COLO205, Jurkat, and HeLa cells, using GRK7 Antibody. The lane on the right is blocked with the synthesized peptide.