Hel-N1 Polyclonal Antibody

    • Catalog No.:YT2124
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Hel-N1
      • Gene Name:
      • ELAVL2
      • Protein Name:
      • ELAV-like protein 2
      • Human Gene Id:
      • 1993
      • Human Swiss Prot No:
      • Q12926
      • Mouse Swiss Prot No:
      • Q60899
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human ELAVL2. AA range:11-60
      • Specificity:
      • Hel-N1 Polyclonal Antibody detects endogenous levels of Hel-N1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ELAVL2;HUB;ELAV-like protein 2;ELAV-like neuronal protein 1;Hu-antigen B;HuB;Nervous system-specific RNA-binding protein Hel-N1
      • Observed Band(KD):
      • 38kD
      • Background:
      • ELAV like RNA binding protein 2(ELAVL2) Homo sapiens The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
      • Function:
      • function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.,similarity:Belongs to the RRM elav family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Brain; neural-specific.,
      • Subcellular Location:
      • nucleoplasm,
      • Expression:
      • Brain; neural-specific.
      • Products Images
      • Western Blot analysis of various cells using Hel-N1 Polyclonal Antibody
      • Western blot analysis of lysates from HepG2 and Jurkat cells, using ELAVL2 Antibody. The lane on the right is blocked with the synthesized peptide.