IFITM3 Polyclonal Antibody
- Catalog No.:YT2277
- Applications:WB;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- IFITM3
- Gene Name:
- IFITM3
- Protein Name:
- Interferon-induced transmembrane protein 3
- Human Gene Id:
- 10410
- Human Swiss Prot No:
- Q01628
- Mouse Swiss Prot No:
- Q9CQW9
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human IFM3. AA range:1-50
- Specificity:
- IFITM3 Polyclonal Antibody detects endogenous levels of IFITM3 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- IFITM3;Interferon-induced transmembrane protein 3;Dispanin subfamily A member 2b;DSPA2b;Interferon-inducible protein 1-8U
- Observed Band(KD):
- 15kD
- Background:
- The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012],
- Function:
- induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
- Subcellular Location:
- Cell membrane ; Single-pass type II membrane protein . Late endosome membrane ; Single-pass type II membrane protein . Early endosome membrane ; Single-pass type II membrane protein. Lysosome membrane ; Single-pass type II membrane protein . Cytoplasm, perinuclear region . Co-localizes with BRI3 isoform 1 at the perinuclear region. .
- Expression:
- Brain,Cervix,Vascular endothelial cell,
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