JIK Polyclonal Antibody
- Catalog No.:YT2433
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- JIK
- Fields:
- >>MAPK signaling pathway
- Gene Name:
- TAOK3
- Protein Name:
- Serine/threonine-protein kinase TAO3
- Human Gene Id:
- 51347
- Human Swiss Prot No:
- Q9H2K8
- Mouse Gene Id:
- 330177
- Mouse Swiss Prot No:
- Q8BYC6
- Rat Gene Id:
- 304530
- Rat Swiss Prot No:
- Q53UA7
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580
- Specificity:
- JIK Polyclonal Antibody detects endogenous levels of JIK protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- TAOK3;DPK;JIK;KDS;MAP3K18;Serine/threonine-protein kinase TAO3;Cutaneous T-cell lymphoma-associated antigen HD-CL-09;CTCL-associated antigen HD-CL-09;Dendritic cell-derived protein kinase;JNK/SAPK-inhibitory kinase;Jun kinase-inhi
- Observed Band(KD):
- 110kD
- Background:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,
- Function:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,
- Subcellular Location:
- Cytoplasm . Cell membrane ; Peripheral membrane protein . Also localized to the peripheral cell membrane.
- Expression:
- Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using JIK Polyclonal Antibody
- Western Blot analysis of Jurkat cells using JIK Polyclonal Antibody
- Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).