• Target：
• Jun D

• Fields：
• >>MAPK signaling pathway;>>Osteoclast differentiation;>>IL-17 signaling pathway;>>Parathyroid hormone synthesis, secretion and action

• Gene Name：
• JUND

• Protein Name：
• Transcription factor jun-D

• Human Gene Id：
• 3727

• Human Swiss Prot No：
• P17535

• Mouse Gene Id：
• 16478

• Mouse Swiss Prot No：
• P15066

• Rat Gene Id：
• 24518

• Rat Swiss Prot No：
• P52909

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human JunD. AA range:222-271

• Specificity：
• Jun D Polyclonal Antibody detects endogenous levels of Jun D protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• JUND;Transcription factor jun-D

• Observed Band(KD)：
• 38kD

• Background：
• The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013],

• Function：
• function:Binds an AP-1 site and upon cotransfection stimulates the activity of a promoter that bears an AP-1 site.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer.,

• Subcellular Location：
• Nucleus.

• Expression：
• Epithelium,Spleen,

JunD functions as a transcription factor of IL-10 to regulate bacterial infectious inflammation in grass carp (Ctenopharyngodon idella) INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES Hong Yang IF Grass carp 1:200 spleen leukocytes

Exercise Alleviates Fluoride-Induced Learning and Memory Impairment in Mice: Role of miR-206-3p and PREG BIOLOGICAL TRACE ELEMENT RESEARCH Chai Lei WB Mouse 1:1000 HT-22 cell

A specific GAGTT insertion/deletion variation in the IL-10 gene promoter alters the disease resistance of grass carp AQUACULTURE Hong Yang WB,Pull Down Fish 1:1000 spleen tissue

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