LTK Polyclonal Antibody
- Catalog No.:YT2598
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- LTK
- Gene Name:
- LTK
- Protein Name:
- Leukocyte tyrosine kinase receptor
- Human Gene Id:
- 4058
- Human Swiss Prot No:
- P29376
- Mouse Gene Id:
- 17005
- Mouse Swiss Prot No:
- P08923
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human LTK. AA range:206-255
- Specificity:
- LTK Polyclonal Antibody detects endogenous levels of LTK protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- LTK;TYK1;Leukocyte tyrosine kinase receptor;Protein tyrosine kinase 1
- Observed Band(KD):
- 92kD
- Background:
- leukocyte receptor tyrosine kinase(LTK) Homo sapiens The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
- Function:
- alternative products:Additional isoforms seem to exist,catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:The exact function of this protein is not known. It is probably a receptor with a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in non-hematopoietic cell lines and T- and B-cell lines.,
- Subcellular Location:
- Cell membrane ; Single-pass type I membrane protein .
- Expression:
- Expressed in non-hematopoietic cell lines and T- and B-cell lines.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from Jurkat cells, using LTK Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HeLa cells using LTK antibody.
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).