Maspin Polyclonal Antibody
- Catalog No.:YT2657
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- Maspin
- Fields:
- >>p53 signaling pathway;>>MicroRNAs in cancer
- Gene Name:
- SERPINB5
- Protein Name:
- Serpin B5
- Human Gene Id:
- 5268
- Human Swiss Prot No:
- P36952
- Mouse Gene Id:
- 20724
- Mouse Swiss Prot No:
- P70124
- Rat Gene Id:
- 116589
- Rat Swiss Prot No:
- P70564
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140
- Specificity:
- Maspin Polyclonal Antibody detects endogenous levels of Maspin protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- SERPINB5;PI5;Serpin B5;Maspin;Peptidase inhibitor 5;PI-5
- Observed Band(KD):
- 40kD
- Background:
- function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
- Function:
- function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
- Subcellular Location:
- Secreted, extracellular space.
- Expression:
- Normal mammary epithelial cells.
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- July 13-2018
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- July 13-2018
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- July 13-2018
- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using Maspin Polyclonal Antibody
- Western blot analysis of lysates from HeLa cells, using Serpin B5 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HeLa cells using PARP2 antibody.
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).