Nop132 Polyclonal Antibody

    • Catalog No.：YT3165
    • Applications：WB;IHC;IF;ELISA
    • Reactivity：Human;Mouse
      • Target：
      • Nop132
      • Gene Name：
      • NOL8
      • Protein Name：
      • Nucleolar protein 8
      • Human Swiss Prot No：
      • Q76FK4
      • Mouse Swiss Prot No：
      • Q3UHX0
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from human NOL8. AA range:1118-1167
      • Specificity：
      • Nop132 Polyclonal Antibody detects endogenous levels of Nop132 protein.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • NOL8;C9orf34;NOP132;Nucleolar protein 8;Nucleolar protein Nop132
      • Observed Band(KD)：
      • 130kD
      • Background：
      • NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 [PubMed 14660641]).[supplied by OMIM, Mar 2008],
      • Function：
      • function:Plays an essential role in the survival of diffuse-type gastric cancer cells. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.,induction:Up-regulated in diffuse-type gastric cancers.,PTM:Phosphorylated.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with the GTP form of RRAGA, RRAGC and RRAGD. Interacts with NIP7.,tissue specificity:Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.,
      • Subcellular Location：
      • Nucleus, nucleolus . Localizes in the nucleolar-organizing region during ribosome biogenesis.
      • Expression：
      • Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.
      • Products Images
      • Western Blot analysis of 3T3 cells using Nop132 Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
      • Western Blot analysis of NIH-3T3 cells using Nop132 Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
      • Western blot analysis of NOL8 Antibody. The lane on the right is blocked with the NOL8 peptide.
      • Immunohistochemistryt analysis of paraffin-embedded human brain, using NOL8 Antibody. The lane on the right is blocked with the NOL8 peptide.
      • Western blot analysis of the lysates from HepG2 cells using NOL8 antibody.

      Attributes

      • Code：
      • YT3165
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2025-01-09
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