• Target：
• NT5C1A

• Fields：
• >>Purine metabolism;>>Pyrimidine metabolism;>>Nicotinate and nicotinamide metabolism;>>Metabolic pathways;>>Nucleotide metabolism

• Gene Name：
• NT5C1A

• Protein Name：
• Cytosolic 5'-nucleotidase 1A

• Human Gene Id：
• 84618

• Human Swiss Prot No：
• Q9BXI3

• Mouse Gene Id：
• 230718

• Mouse Swiss Prot No：
• A3KFX0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NT5C1A. AA range:151-200

• Specificity：
• NT5C1A Polyclonal Antibody detects endogenous levels of NT5C1A protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NT5C1A;Cytosolic 5'-nucleotidase 1A;cN1A;Cytosolic 5'-nucleotidase IA;cN-I;cN-IA

• Observed Band(KD)：
• 41kD

• Background：
• Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008],

• Function：
• catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.,similarity:Belongs to the 5'-nucleotidase type 3 family.,tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.,

• Subcellular Location：
• Cytoplasm.

• Expression：
• Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.

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