Rab 18 Polyclonal Antibody
- Catalog No.:YT3920
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- Rab 18
- Gene Name:
- RAB18
- Protein Name:
- Ras-related protein Rab-18
- Human Gene Id:
- 22931
- Human Swiss Prot No:
- Q9NP72
- Mouse Gene Id:
- 19330
- Mouse Swiss Prot No:
- P35293
- Rat Gene Id:
- 307039
- Rat Swiss Prot No:
- Q5EB77
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152
- Specificity:
- Rab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- RAB18;Ras-related protein Rab-18
- Observed Band(KD):
- 28kD
- Background:
- The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
- Function:
- function:Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
- Subcellular Location:
- Apical cell membrane . Lipid droplet .
- Expression:
- Ubiquitous.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of MCF-7 cells using Rab 18 Polyclonal Antibody
- Western blot analysis of lysates from MCF-7 and HUVEC cells, using RAB18 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HepG2 cells using RAB18 antibody.
- Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).