• Target：
• Rab 2B

• Gene Name：
• RAB2B

• Protein Name：
• Ras-related protein Rab-2B

• Human Gene Id：
• 84932

• Human Swiss Prot No：
• Q8WUD1

• Mouse Gene Id：
• 76338

• Mouse Swiss Prot No：
• P59279

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human RAB2B. AA range:103-152

• Specificity：
• Rab 2B Polyclonal Antibody detects endogenous levels of Rab 2B protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• RAB2B;Ras-related protein Rab-2B

• Observed Band(KD)：
• 24kD

• Background：
• Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006],

• Function：
• function:Required for protein transport from the endoplasmic reticulum to the Golgi complex .,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.,

• Subcellular Location：
• Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endoplasmic reticulum membrane ; Lipid-anchor . Golgi apparatus membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle, acrosome . Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid. .

• Expression：
• Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.

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