Rab 38 Polyclonal Antibody
- Catalog No.:YT3933
- Applications:WB;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- Rab 38
- Gene Name:
- RAB38
- Protein Name:
- Ras-related protein Rab-38
- Human Gene Id:
- 23682
- Human Swiss Prot No:
- P57729
- Mouse Gene Id:
- 72433
- Mouse Swiss Prot No:
- Q8QZZ8
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129
- Specificity:
- Rab 38 Polyclonal Antibody detects endogenous levels of Rab 38 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- RAB38;Ras-related protein Rab-38;Melanoma antigen NY-MEL-1
- Observed Band(KD):
- 26kD
- Background:
- function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.,PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in melanocytes.,
- Function:
- function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.,PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in melanocytes.,
- Subcellular Location:
- Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). .
- Expression:
- Expressed in melanocytes.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from Jurkat cells, using RAB38 Antibody. The lane on the right is blocked with the synthesized peptide.
- Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).