Rab 5C Polyclonal Antibody

    • Catalog No.:YT3936
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Rab 5C
      • Fields:
      • >>Ras signaling pathway;>>Endocytosis;>>Phagosome;>>Vasopressin-regulated water reabsorption;>>Salmonella infection;>>Amoebiasis;>>Tuberculosis
      • Gene Name:
      • RAB5C
      • Protein Name:
      • Ras-related protein Rab-5C
      • Human Gene Id:
      • 5878
      • Human Swiss Prot No:
      • P51148
      • Mouse Swiss Prot No:
      • P35278
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RAB5C. AA range:122-171
      • Specificity:
      • Rab 5C Polyclonal Antibody detects endogenous levels of Rab 5C protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RAB5C;RABL;Ras-related protein Rab-5C;L1880;RAB5L
      • Observed Band(KD):
      • 30kD
      • Background:
      • Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010],
      • Function:
      • function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds EEA1.,
      • Subcellular Location:
      • Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
      • Expression:
      • Brain,Lung,
      • Products Images
      • Western blot analysis of lysates from LOVO, HeLa, and Jurkat cells, using RAB5C Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from 293 cells using RAB5C antibody.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).