Rabaptin-5β Polyclonal Antibody

    • Catalog No.:YT3948
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Rabaptin-5β
      • Gene Name:
      • RABEP2
      • Protein Name:
      • Rab GTPase-binding effector protein 2
      • Human Swiss Prot No:
      • Q9H5N1
      • Mouse Swiss Prot No:
      • Q91WG2
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RABEP2. AA range:353-402
      • Specificity:
      • Rabaptin-5β Polyclonal Antibody detects endogenous levels of Rabaptin-5β protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RABEP2;RABPT5B;Rab GTPase-binding effector protein 2;Rabaptin-5beta
      • Observed Band(KD):
      • 64kD
      • Background:
      • function:Plays a role in membrane trafficking and in homotypic early endosome fusion.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The dimer binds RAB5A that has been activated by GTP-binding.,
      • Function:
      • function:Plays a role in membrane trafficking and in homotypic early endosome fusion.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The dimer binds RAB5A that has been activated by GTP-binding.,
      • Subcellular Location:
      • Cytoplasm . Early endosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body .
      • Expression:
      • Hepatoma,Mammary gland,Testis,
      • Products Images
      • Western Blot analysis of various cells using Rabaptin-5β Polyclonal Antibody
      • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Western blot analysis of lysates from HeLa, Jurkat, 293, and HUVEC cells, using RABEP2 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HeLa cells using RABEP2 antibody.