• Target：
• Rag B

• Fields：
• >>Autophagy - animal;>>mTOR signaling pathway;>>Shigellosis

• Gene Name：
• RRAGB

• Protein Name：
• Ras-related GTP-binding protein B

• Human Gene Id：
• 10325

• Human Swiss Prot No：
• Q5VZM2

• Mouse Gene Id：
• 245670

• Mouse Swiss Prot No：
• Q6NTA4

• Rat Gene Id：
• 1.0091e+008

• Rat Swiss Prot No：
• Q63487

• Immunogen：
• Synthesized peptide derived from Rag B . at AA range: 50-130

• Specificity：
• Rag B Polyclonal Antibody detects endogenous levels of Rag B protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• RRAGB;Ras-related GTP-binding protein B;Rag B;RagB

• Molecular Weight(Da)：
• 43kD

• Background：
• Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],

• Function：
• function:Involved in the RCC1/Ran-GTPase pathway. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subunit:The short isoform binds GTP (By similarity). Interacts with RRAGC and RRAGD.,

• Subcellular Location：
• Cytoplasm . Lysosome .

• Expression：
• Adipose tissue,Brain,Skin,

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