• Target：
• Rho GDIγ

• Fields：
• >>Neurotrophin signaling pathway;>>Vasopressin-regulated water reabsorption

• Gene Name：
• ARHGDIG

• Protein Name：
• Rho GDP-dissociation inhibitor 3

• Human Gene Id：
• 398

• Human Swiss Prot No：
• Q99819

• Mouse Swiss Prot No：
• Q62160

• Immunogen：
• Synthesized peptide derived from Rho GDIγ . at AA range: 110-190

• Specificity：
• Rho GDIγ Polyclonal Antibody detects endogenous levels of Rho GDIγ protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ARHGDIG;Rho GDP-dissociation inhibitor 3;Rho GDI 3;Rho-GDI gamma

• Observed Band(KD)：
• 25kD

• Background：
• The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010],

• Function：
• function:Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.,similarity:Belongs to the Rho GDI family.,tissue specificity:Primarily expressed in pancreas and brain.,

• Subcellular Location：
• Cytoplasm.

• Expression：
• Primarily expressed in pancreas and brain.

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