• Target：
• StARD13

• Gene Name：
• STARD13

• Protein Name：
• StAR-related lipid transfer protein 13

• Human Gene Id：
• 90627

• Human Swiss Prot No：
• Q9Y3M8

• Mouse Gene Id：
• 243362

• Mouse Swiss Prot No：
• Q923Q2

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human STA13. AA range:101-150

• Specificity：
• StARD13 Polyclonal Antibody detects endogenous levels of StARD13 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• STARD13;DLC2;GT650;StAR-related lipid transfer protein 13;46H23.2;Deleted in liver cancer 2 protein;DLC-2;Rho GTPase-activating protein;START domain-containing protein 13;StARD13

• Observed Band(KD)：
• 125kD

• Background：
• This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],

• Function：
• function:GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 1 START domain.,subunit:Homodimer. Interacts with TAX1BP1.,tissue specificity:Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.,

• Subcellular Location：
• Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet.

• Expression：
• Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.

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