• Target：
• STEAP1

• Fields：
• >>Mineral absorption

• Gene Name：
• STEAP1

• Protein Name：
• Metalloreductase STEAP1

• Human Gene Id：
• 26872

• Human Swiss Prot No：
• Q9UHE8

• Mouse Swiss Prot No：
• Q9CWR7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human STEAP1. AA range:31-80

• Specificity：
• STEAP1 Polyclonal Antibody detects endogenous levels of STEAP1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• STEAP1;PRSS24;STEAP;Metalloreductase STEAP1;Six-transmembrane epithelial antigen of prostate 1

• Observed Band(KD)：
• 36kD

• Background：
• This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008],

• Function：
• cofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitously expressed. Highly expressed in prostate tumors.,

• Subcellular Location：
• Endosome membrane ; Multi-pass membrane protein .

• Expression：
• Ubiquitously expressed. Highly expressed in prostate tumors.

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