• Target：
• Syndecan-2

• Fields：
• >>Cell adhesion molecules;>>Malaria;>>Proteoglycans in cancer;>>Fluid shear stress and atherosclerosis

• Gene Name：
• SDC2

• Protein Name：
• Syndecan-2

• Human Gene Id：
• 6383

• Human Swiss Prot No：
• P34741

• Mouse Swiss Prot No：
• P43407

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human SDC2. AA range:81-130

• Specificity：
• Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SDC2;HSPG1;Syndecan-2;SYND2;Fibroglycan;Heparan sulfate proteoglycan core protein;HSPG;CD antigen CD362

• Observed Band(KD)：
• 22kD

• Background：
• The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008],

• Function：
• function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,

• Subcellular Location：
• Membrane; Single-pass type I membrane protein.

• Expression：
• Brain,Embryo,Lung fibroblast,Muscle,Testis,

MiR-20a-5p represses the multi-drug resistance of osteosarcoma by targeting the SDC2 gene. Cancer Cell International Cancer Cell Int. 2017 Dec;17(1):1-11 WB Human SJSA-1 cell,G-292 cell

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