• Target：
• TAB182

• Gene Name：
• TNKS1BP1

• Protein Name：
• 182 kDa tankyrase-1-binding protein

• Human Gene Id：
• 85456

• Human Swiss Prot No：
• Q9C0C2

• Mouse Gene Id：
• 228140

• Mouse Swiss Prot No：
• P58871

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TNKS1BP1. AA range:1601-1650

• Specificity：
• TAB182 Polyclonal Antibody detects endogenous levels of TAB182 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TNKS1BP1;KIAA1741;TAB182;182 kDa tankyrase-1-binding protein

• Observed Band(KD)：
• 150kD

• Background：
• PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.,

• Function：
• PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.,

• Subcellular Location：
• Nucleus. Cytoplasm, cytoskeleton. Chromosome. Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.

• Expression：
• Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.

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