TReP-132 Polyclonal Antibody

    • Catalog No.:YT4732
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • TReP-132
      • Gene Name:
      • TRERF1
      • Protein Name:
      • Transcriptional-regulating factor 1
      • Human Swiss Prot No:
      • Q96PN7
      • Mouse Swiss Prot No:
      • Q8BXJ2
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human TREF1. AA range:1071-1120
      • Specificity:
      • TReP-132 Polyclonal Antibody detects endogenous levels of TReP-132 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • TRERF1;BCAR2;RAPA;TREP132;Transcriptional-regulating factor 1;Breast cancer anti-estrogen resistance 2;Transcriptional-regulating protein 132;Zinc finger protein rapa;Zinc finger transcription factor TReP-132
      • Molecular Weight(Da):
      • 132kD
      • Background:
      • This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
      • Function:
      • function:Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.,similarity:Contains 1 ELM2 domain.,similarity:Contains 1 SANT domain.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with CREBBP and EP300.,tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells.
      • Products Images
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TREF1 Antibody. The picture on the right is blocked with the synthesized peptide.