• Target：
• USF-2

• Gene Name：
• USF2

• Protein Name：
• Upstream stimulatory factor 2

• Human Gene Id：
• 7392

• Human Swiss Prot No：
• Q15853

• Mouse Gene Id：
• 22282

• Mouse Swiss Prot No：
• Q64705

• Rat Gene Id：
• 81817

• Rat Swiss Prot No：
• Q63665

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human USF2. AA range:196-245

• Specificity：
• USF-2 Polyclonal Antibody detects endogenous levels of USF-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• USF2;BHLHB12;Upstream stimulatory factor 2;Class B basic helix-loop-helix protein 12;bHLHb12;FOS-interacting protein;FIP;Major late transcription factor 2;Upstream transcription factor 2

• Observed Band(KD)：
• 40kD

• Background：
• This gene encodes a member of the basic helix-loop-helix leucine zipper family of transcription factors. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes. [provided by RefSeq, Mar 2016],

• Function：
• alternative products:Additional isoforms seem to exist,function:Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with MAF (By similarity). Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an homodimer or a heterodimer (USF1/USF2). In vivo, the USF1/USF2A heterodimer represents over 66% of the usf binding activity whereas the USF1 and USF2A homodimers represent less than 10%. The USF1/USF2B heterodimer accounted for almost 15% in some cell.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Nucleus.

• Expression：
• Ubiquitous.

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