• Target：
• USP44

• Gene Name：
• USP44

• Protein Name：
• Ubiquitin carboxyl-terminal hydrolase 44

• Human Gene Id：
• 84101

• Human Swiss Prot No：
• Q9H0E7

• Mouse Swiss Prot No：
• Q8C2S0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human USP44. AA range:211-260

• Specificity：
• USP44 Polyclonal Antibody detects endogenous levels of USP44 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• USP44;Ubiquitin carboxyl-terminal hydrolase 44;Deubiquitinating enzyme 44;Ubiquitin thioesterase 44;Ubiquitin-specific-processing protease 44

• Observed Band(KD)：
• 81kD

• Background：
• Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP44 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],

• Function：
• catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBP-type zinc finger.,tissue specificity:Expressed in testis.,

• Subcellular Location：
• Nucleus . Peaks in interphase, with relatively low levels maintained throughout mitosis. .

• Expression：
• Expressed in testis. Expressed at high levels in T-cell acute lymphoblastic leukemia.

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