VPS26B Polyclonal Antibody
- Catalog No.:YT4889
- Applications:WB;ELISA
- Reactivity:Human;Mouse
- Target:
- VPS26B
- Fields:
- >>Endocytosis
- Gene Name:
- VPS26B
- Protein Name:
- Vacuolar protein sorting-associated protein 26B
- Human Gene Id:
- 112936
- Human Swiss Prot No:
- Q4G0F5
- Mouse Gene Id:
- 69091
- Mouse Swiss Prot No:
- Q8C0E2
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
- Specificity:
- VPS26B Polyclonal Antibody detects endogenous levels of VPS26B protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- VPS26B;Vacuolar protein sorting-associated protein 26B;Vesicle protein sorting 26B
- Observed Band(KD):
- 45kD
- Background:
- function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
- Function:
- function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
- Subcellular Location:
- Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). .
- Expression:
- Eye,Lung,Placenta,
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- Antibody-FAQs
- Products Images
- Western Blot analysis of LOVO cells using VPS26B Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Western blot analysis of lysates from LOVO cells, using VPS26B Antibody. The lane on the right is blocked with the synthesized peptide.