WDHD1 Polyclonal Antibody

    • Catalog No.:YT4902
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • WDHD1
      • Gene Name:
      • WDHD1
      • Protein Name:
      • WD repeat and HMG-box DNA-binding protein 1
      • Human Swiss Prot No:
      • O75717
      • Mouse Swiss Prot No:
      • P59328
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human WDHD1. AA range:721-770
      • Specificity:
      • WDHD1 Polyclonal Antibody detects endogenous levels of WDHD1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • WDHD1;AND1;WD repeat and HMG-box DNA-binding protein 1;Acidic nucleoplasmic DNA-binding protein 1;And-1
      • Observed Band(KD):
      • 126kD
      • Background:
      • The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
      • Function:
      • caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Binds DNA with high affinity. May also be involved in protein-protein interactions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HMG box DNA-binding domain.,similarity:Contains 7 WD repeats.,
      • Subcellular Location:
      • Nucleus, nucleoplasm .
      • Expression:
      • Embryonal rhabdomyosarcoma,Epithelium,Fetal brain,Liver,Ski
      • Products Images
      • Western Blot analysis of various cells using WDHD1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of lysates from Jurkat and HepG2 cells, using WDHD1 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).