• Target：
• HGFA

• Gene Name：
• HGFAC

• Protein Name：
• Hepatocyte growth factor activator

• Human Gene Id：
• 3083

• Human Swiss Prot No：
• Q04756

• Mouse Gene Id：
• 54426

• Mouse Swiss Prot No：
• Q9R098

• Immunogen：
• Synthesized peptide derived from the C-terminal region of human HGFA.

• Specificity：
• HGFA Polyclonal Antibody detects endogenous levels of HGFA protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• HGFAC;Hepatocyte growth factor activator;HGF activator;HGFA

• Observed Band(KD)：
• 70kD

• Background：
• This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

• Function：
• caution:It is uncertain whether Met-1 is the initiator.,function:Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 fibronectin type-I domain.,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subcellular location:Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.,subunit:Heterodimer of a short chain and a long chain linked by a disulfide bond.,tissue specificity:Liver.,

• Subcellular Location：
• Secreted. Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.

• Expression：
• Liver.

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