• Target：
• Hepassocin

• Gene Name：
• FGL1

• Protein Name：
• Fibrinogen-like protein 1

• Human Gene Id：
• 2267

• Human Swiss Prot No：
• Q08830

• Mouse Gene Id：
• 234199

• Mouse Swiss Prot No：
• Q71KU9

• Rat Swiss Prot No：
• Q5M8C6

• Immunogen：
• Synthesized peptide derived from the Internal region of human Hepassocin.

• Specificity：
• Hepassocin Polyclonal Antibody detects endogenous levels of Hepassocin protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• FGL1;HFREP1;Fibrinogen-like protein 1;HP-041;Hepassocin;Hepatocyte-derived fibrinogen-related protein 1;HFREP-1;Liver fibrinogen-related protein 1;LFIRE-1

• Observed Band(KD)：
• 36kD

• Background：
• fibrinogen like 1(FGL1) Homo sapiens Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008],

• Function：
• function:Has hepatocyte mitogenic activity.,similarity:Contains 1 fibrinogen C-terminal domain.,subunit:Homodimer.,tissue specificity:Liver specific.,

• Subcellular Location：
• Secreted . Secreted in the blood plasma. .

• Expression：
• Under normal conditions, liver-specific.

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