• Target：
• SCCA1/2

• Fields：
• >>Amoebiasis

• Gene Name：
• SERPINB3/SERPINB4

• Protein Name：
• Serpin B3/Serpin B4

• Human Gene Id：
• 6317

• Human Swiss Prot No：
• P29508

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINB3/4. AA range:111-160

• Specificity：
• SCCA1/2 Polyclonal Antibody detects endogenous levels of SCCA1/2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SERPINB3;SCCA;SCCA1;Serpin B3;Protein T4-A;Squamous cell carcinoma antigen 1;SCCA-1

• Observed Band(KD)：
• 45kD

• Background：
• developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells.,function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).,

• Function：
• developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells.,function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).,

• Subcellular Location：
• Cytoplasm . Seems to also be secreted in plasma by cancerous cells but at a low level.

• Expression：
• Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).

Metformin inhibits mitochondrial dysfunction and apoptosis in cardiomyocytes induced by high glucose via upregulating AMPK activity. EXPERIMENTAL BIOLOGY AND MEDICINE Yuansheng Wu WB,IHC Mouse 1:500,1:1100 skin

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