• Target：
• CD232

• Fields：
• >>Axon guidance

• Gene Name：
• PLXNC1

• Protein Name：
• Plexin-C1

• Human Gene Id：
• 10154

• Human Swiss Prot No：
• O60486

• Mouse Gene Id：
• 54712

• Mouse Swiss Prot No：
• Q9QZC2

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human PLXNC1. AA range:811-860

• Specificity：
• CD232 Polyclonal Antibody detects endogenous levels of CD232 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PLXNC1;VESPR;Plexin-C1;Virus-encoded semaphorin protein receptor;CD232

• Observed Band(KD)：
• 175kD

• Background：
• This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011],

• Function：
• function:Receptor for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of viral semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8.,PTM:N-glycosylated.,similarity:Belongs to the plexin family.,similarity:Contains 1 Sema domain.,tissue specificity:Detected in heart, brain, lung, spleen and placenta.,

• Subcellular Location：
• Membrane ; Single-pass type I membrane protein .

• Expression：
• Detected in heart, brain, lung, spleen and placenta.

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