• Target：
• GDF-7

• Fields：
• >>Cytokine-cytokine receptor interaction;>>TGF-beta signaling pathway;>>Axon guidance;>>Hippo signaling pathway

• Gene Name：
• GDF7

• Protein Name：
• Growth/differentiation factor 7

• Human Gene Id：
• 151449

• Human Swiss Prot No：
• Q7Z4P5

• Mouse Gene Id：
• 238057

• Mouse Swiss Prot No：
• P43029

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370

• Specificity：
• GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GDF7;Growth/differentiation factor 7;GDF-7

• Observed Band(KD)：
• 47kD

• Background：
• This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],

• Function：
• function:May play an active role in the motor area of the primate neocortex.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,

• Subcellular Location：
• Secreted .

• Expression：
• Testis,

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