SCGF Polyclonal Antibody
- Catalog No.:YT5719
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- SCGF
- Gene Name:
- CLEC11A
- Protein Name:
- C-type lectin domain family 11 member A
- Human Gene Id:
- 6320
- Human Swiss Prot No:
- Q9Y240
- Mouse Gene Id:
- 20256
- Mouse Swiss Prot No:
- O88200
- Rat Gene Id:
- 29313
- Rat Swiss Prot No:
- O88201
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the N-terminal region of human CLEC11A. AA range:1-50
- Specificity:
- SCGF Polyclonal Antibody detects endogenous levels of SCGF protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CLEC11A;CLECSF3;LSLCL;SCGF;C-type lectin domain family 11 member A;C-type lectin superfamily member 3;Lymphocyte secreted C-type lectin;Stem cell growth factor;p47
- Observed Band(KD):
- 30kD
- Background:
- This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008],
- Function:
- developmental stage:In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.,function:Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.,online information:Stem cell growth factor,PTM:O-glycosylated. Probably sulfated on the O-glycans.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.,
- Subcellular Location:
- Cytoplasm . Secreted .
- Expression:
- Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
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- Antibody-FAQs
- Products Images
- Western blot analysis of MOUSE-SPLEEN RAT-SPLEEN using CLEC11A antibody. Antibody was diluted at 1:2000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100