• Target：
• IL-1F10

• Fields：
• >>Cytokine-cytokine receptor interaction

• Gene Name：
• IL1F10

• Protein Name：
• Interleukin-1 family member 10

• Human Gene Id：
• 84639

• Human Swiss Prot No：
• Q8WWZ1

• Mouse Gene Id：
• 215274

• Mouse Swiss Prot No：
• Q8R459

• Immunogen：
• Synthesized peptide derived from Interleukin-1 family member 10 at AA range: 101-150

• Specificity：
• IL-1F10 Polyclonal Antibody detects endogenous levels of IL-1F10 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• IL1F10;FIL1T;IL1HY2;FKSG75;Interleukin-1 family member 10;IL-1F10;FIL1 theta;Interleukin-1 HY2;IL-1HY2;Interleukin-1 theta;IL-1 theta

• Observed Band(KD)：
• 17kD

• Background：
• The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],

• Function：
• function:Binds soluble IL-1 receptor type 1.,online information:Interleukin-1 entry,similarity:Belongs to the IL-1 family.,tissue specificity:Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.,

• Subcellular Location：
• Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .

• Expression：
• Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.

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