• Target：
• CMTM8

• Gene Name：
• CMTM8

• Protein Name：
• CKLF-like MARVEL transmembrane domain-containing protein 8

• Human Gene Id：
• 152189

• Human Swiss Prot No：
• Q8IZV2

• Mouse Gene Id：
• 70031

• Mouse Swiss Prot No：
• Q9CZR4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human CMTM8. AA range:101-150

• Specificity：
• CMTM8 Polyclonal Antibody detects endogenous levels of CMTM8 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CMTM8;CKLFSF8;CKLF-like MARVEL transmembrane domain-containing protein 8;Chemokine-like factor superfamily member 8

• Observed Band(KD)：
• 20kD

• Background：
• This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],

• Function：
• similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in liver and pancreas.,

• Subcellular Location：
• [Isoform 1]: Membrane; Multi-pass membrane protein.; [Isoform 2]: Cytoplasm. Nucleus.

• Expression：
• Highly expressed in liver and pancreas.

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