CTGF Polyclonal Antibody

  • Catalog No.：YT6207
  • Applications：IHC;IF;WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • CTGF
    • Fields：
    • >>Apelin signaling pathway;>>Hippo signaling pathway
    • Gene Name：
    • CTGF CCN2 HCS24 IGFBP8
    • Protein Name：
    • CTGF
    • Human Gene Id：
    • 1490
    • Human Swiss Prot No：
    • P29279
    • Immunogen：
    • Synthesized peptide derived from human CTGF AA range: 130-210
    • Specificity：
    • This antibody detects endogenous levels of human CTGF
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • IHC 1:50-200, WB 1:500-2000. IF 1:50-200
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Connective tissue growth factor (CCN family member 2;Hypertrophic chondrocyte-specific protein 24;Insulin-like growth factor-binding protein 8;IBP-8;IGF-binding protein 8;IGFBP-8)
    • Observed Band(KD)：
    • 37kD
    • Background：
    • The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009],
    • Function：
    • function:Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.,similarity:Belongs to the CCN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 TSP type-1 domain.,similarity:Contains 1 VWFC domain.,subunit:Monomer.,
    • Subcellular Location：
    • Secreted, extracellular space, extracellular matrix . Secreted .
    • Expression：
    • Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.

    Attributes

    • Code：
    • YT6207
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2025-01-24
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