A-FABP rabbit pAb

  • Catalog No.:YT7833
  • Applications:WB;ELISA
  • Reactivity:Human;Rat;Mouse;
    • Target:
    • A-FABP
    • Fields:
    • >>PPAR signaling pathway;>>Regulation of lipolysis in adipocytes
    • Gene Name:
    • FABP4
    • Protein Name:
    • A-FABP
    • Human Gene Id:
    • 2167
    • Human Swiss Prot No:
    • P15090
    • Mouse Swiss Prot No:
    • P04117
    • Immunogen:
    • Synthesized peptide derived from human A-FABP AA range: 80-120
    • Specificity:
    • This antibody detects endogenous levels of Human A-FABP
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Fatty acid-binding protein, adipocyte (Adipocyte lipid-binding protein;ALBP;Adipocyte-type fatty acid-binding protein;A-FABP;AFABP;Fatty acid-binding protein 4)
    • Molecular Weight(Da):
    • 15kD
    • Background:
    • FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008],
    • Function:
    • domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,subcellular location:Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.,subunit:Homodimer. Interacts with PPARG (By similarity). Monomer.,
    • Subcellular Location:
    • Cytoplasm . Nucleus . Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. .