RBP rabbit pAb

  • Catalog No.：YT7861
  • Applications：WB;IHC
  • Reactivity：Human;Rat;Mouse;
    • Target：
    • RBP
    • Gene Name：
    • RBP4 PRO2222
    • Protein Name：
    • RBP
    • Human Gene Id：
    • 5950
    • Human Swiss Prot No：
    • P02753
    • Mouse Swiss Prot No：
    • Q00724
    • Immunogen：
    • Synthesized peptide derived from human RBP AA range: 11-60
    • Specificity：
    • This antibody detects endogenous levels of Human RBP
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000;IHC 1:50-300
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Retinol-binding protein 4 (Plasma retinol-binding protein;PRBP;RBP) [Cleaved into: Plasma retinol-binding protein(1-182);Plasma retinol-binding protein(1-181);Plasma retinol-binding protein(1-179);Plasma retinol-binding protein(1-176)]
    • Molecular Weight(Da)：
    • 22kD
    • Background：
    • retinol binding protein 4(RBP4) Homo sapiens This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008],
    • Function：
    • disease:A deficiency of vitamin A blocks secretion of the binding protein post-translationally and results in defective delivery and supply of vitamin to the epidermal cells (a condition associated with a dermatosis).,disease:Defects in RBP4 are a cause of retinol-binding protein deficiency [MIM:180250]. This condition causes night vision problems. It produces a typical "fundus xerophthalmicus," featuring a progressed atrophy of the retinal pigment epithelium.,function:Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.,mass spectrometry: PubMed:12237133,mass spectrometry: PubMed:7666002,online information:Retina International's Scientific Newsletter,online information:Retinol-binding protein 4 entry,similarity:Belongs to the calycin superfamil
    • Subcellular Location：
    • Secreted .
    • Expression：
    • Detected in blood plasma and in urine (at protein level).

    Attributes

    • Code：
    • YT7861
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-11-23
    Order

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