Phospho PKD2 (S876) Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA1415C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • PRKD2
    • Human Swiss Prot No：
    • Q9BZL6
    • Mouse Swiss Prot No：
    • Q8BZ03
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by diacylglycerol and phorbol esters.,function:Calcium-independent, phospholipid-dependent, serine- and threonine-specific protein kinase.,PTM:Autophosphorylated. Phorbol esters stimulates autophosphorylation. Phosphorylation of Ser-876 correlates with the activation status of the kinase.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,tissue specificity:Widely expressed.,
    • Function：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, phosphorylation,
    • Subcellular Location：
    • Cytoplasm . Cell membrane . Nucleus . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation. Accumulates in the nucleus upon CK1-mediated phosphorylation after activation of G-protein-coupled receptors. Nuclear accumulation is regulated by blocking nuclear export of active PRKD2 rather than by increasing import. .
    • Expression：
    • Widely expressed.

    Attributes

    • Code：
    • KA1415C
    • Size
    • 96 / well
    • Price$：
    • 470
    • Delivery：
    • 2025-01-10
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