Total AKAP 149 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3840C
- Applications:ELISA
- Reactivity:Human
- Gene Name:
- AKAP1
- Human Gene Id:
- 8165
- Human Swiss Prot No:
- Q92667
- Mouse Swiss Prot No:
- O08715
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84)
- Detection Method:
- Colorimetric
- Background:
- domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.,similarity:Contains 1 KH domain.,similarity:Contains 1 Tudor domain.,tissue specificity:AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma.,
- Subcellular Location:
- Mitochondrion outer membrane . Mitochondrion .
- Expression:
- Isoform 1 is detected in thymus, prostate, testis, ovary, colon and small intestine (PubMed:8769136). Isoform 2 is highly expressed in testis and detected at much lower levels in kidney, pancreas, liver, lung and brain (PubMed:7499250).
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