Total AKAP 149 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3840C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • AKAP1
    • Human Gene Id:
    • 8165
    • Human Swiss Prot No:
    • Q92667
    • Mouse Swiss Prot No:
    • O08715
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84)
    • Detection Method:
    • Colorimetric
    • Background:
    • domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.,similarity:Contains 1 KH domain.,similarity:Contains 1 Tudor domain.,tissue specificity:AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma.,
    • Subcellular Location:
    • Mitochondrion outer membrane . Mitochondrion .
    • Expression:
    • Isoform 1 is detected in thymus, prostate, testis, ovary, colon and small intestine (PubMed:8769136). Isoform 2 is highly expressed in testis and detected at much lower levels in kidney, pancreas, liver, lung and brain (PubMed:7499250).