Total OXSR1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4207C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • OXSR1
    • Human Gene Id:
    • 9943
    • Human Swiss Prot No:
    • O95747
    • Mouse Swiss Prot No:
    • Q6P9R2
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:By autophosphorylation on threonine.,function:Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.,tissue specificity:Ubiquitously expressed in all tissue examined.,
    • Function:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, response to oxidative stress, intracellular signaling cascade, protein kinase cascade, phosphorylation,
    • Subcellular Location:
    • Cytoplasm .
    • Expression:
    • Ubiquitously expressed in all tissue examined.