Total Rhodopsin Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4269C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • OPSD
    • Human Gene Id：
    • 6010
    • Human Swiss Prot No：
    • P08100
    • Mouse Swiss Prot No：
    • P15409
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Rhodopsin (Opsin-2)
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:Defects in RHO are a cause of retinitis pigmentosa autosomal recessive (ARRP) [MIM:268000].,disease:Defects in RHO are the cause of congenital stationary night blindness autosomal dominant type 1 (CSNBAD1) [MIM:610445]; also known as rhodopsin-related congenital stationary night blindness. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision.,disease:Defects in RHO are the cause of retinitis pigmentosa type 4 (RP4) [MIM:180380]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP4 inheritance is autosomal dominant.,function:Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.,online information:Retina International's Scientific Newsletter,online information:Rhodopsin entry,online information:Rhodopsin mutations page,PTM:Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.,similarity:Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.,tissue specificity:Rod shaped photoreceptor cells which mediates vision in dim light.,
    • Function：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, sensory perception, visual perception, phototransduction, phototransduction, visible light, response to radiation, response to light stimulus,detection of external stimulus, detection of abiotic stimulus, detection of light stimulus, detection of visible light,rhodopsin mediated phototransduction, response to abiotic stimulus, rhodopsin mediated signaling pathway,phosphorylation, protein-chromophore linkage, neurological system process, cognition, detection of stimulus involved in sensory perception, detection of light stimulus involved in visual perception, sensory perception of light stimulus,detection of light stimulus involved in sensory perception, detection of stimulus,
    • Subcellular Location：
    • Membrane ; Multi-pass membrane protein . Cell projection, cilium, photoreceptor outer segment . Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia. .
    • Expression：
    • Rod shaped photoreceptor cells which mediate vision in dim light.

    Attributes

    • Code：
    • KA4269C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-08
    Order

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