• Target：
• EphA10

• Gene Name：
• EPHA10

• Protein Name：
• Ephrin type-A receptor 10

• Human Gene Id：
• 284656

• Human Swiss Prot No：
• Q5JZY3

• Mouse Swiss Prot No：
• Q8BYG9

• Immunogen：
• Purified recombinant fragment of human EphA10 expressed in E. Coli.

• Specificity：
• EphA10 Monoclonal Antibody detects endogenous levels of EphA10 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• EPHA10;Ephrin type-A receptor 10

• Molecular Weight(Da)：
• 110kD

• References：
• 1. Biochem Cell Biol. 2011 Apr;89(2):115-29.
  2. Leuk Res. 2009 Mar;33(3):395-406.

• Background：
• Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008],

• Function：
• catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,domain:The protein kinase domain is predicted to be catalytically inactive.,function:Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Mainly expressed in testis.,

• Subcellular Location：
• [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .

• Expression：
• Mainly expressed in testis.

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