• Target：
• Syndecan-4

• Fields：
• >>ECM-receptor interaction;>>Cell adhesion molecules;>>Proteoglycans in cancer;>>Fluid shear stress and atherosclerosis

• Gene Name：
• SDC4

• Protein Name：
• Syndecan-4

• Human Gene Id：
• 6385

• Human Swiss Prot No：
• P31431

• Mouse Gene Id：
• 20971

• Mouse Swiss Prot No：
• O35988

• Rat Gene Id：
• 24771

• Rat Swiss Prot No：
• P34901

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human Syndecan4 around the phosphorylation site of Ser179. AA range:145-194

• Specificity：
• Phospho-Syndecan-4 (S179) Polyclonal Antibody detects endogenous levels of Syndecan-4 protein only when phosphorylated at S179.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SDC4;Syndecan-4;SYND4;Amphiglycan;Ryudocan core protein

• Molecular Weight(Da)：
• 22kD

• Background：
• The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008],

• Function：
• function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Homodimer. Interacts with CDCP1, with GIPC PDZ domain and with NUDT16L1/SDOS (By similarity). Interacts with SDCBP.,tissue specificity:Expressed in epithelial and fibroblastic cells.,

• Subcellular Location：
• [Isoform 1]: Membrane ; Single-pass type I membrane protein . Secreted . Shedding of the ectodomain produces a soluble form. .; [Isoform 2]: Secreted.

• Expression：
• Expressed in epithelial and fibroblastic cells.

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