BCA3 Polyclonal Antibody
- Catalog No.:YT0462
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- BCA3
- Gene Name:
- AKIP1
- Protein Name:
- A-kinase-interacting protein 1
- Human Gene Id:
- 56672
- Human Swiss Prot No:
- Q9NQ31
- Mouse Swiss Prot No:
- Q9JJR5
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human BCA3. AA range:111-160
- Specificity:
- BCA3 Polyclonal Antibody detects endogenous levels of BCA3 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- AKIP1;BCA3;C11orf17;A-kinase-interacting protein 1;Breast cancer-associated gene 3 protein;PKA-interacting protein;Proline-rich protein BCA3
- Observed Band(KD):
- 26kD
- Background:
- This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
- Function:
- subcellular location:Locates to punctate spots.,subunit:Interacts with PRKACA.,tissue specificity:Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.,
- Subcellular Location:
- Nucleus . Locates to punctate spots.
- Expression:
- Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using BCA3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
- Immunohistochemistry analysis of paraffin-embedded human heart tissue, using BCA3 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from Jurkat cells, using BCA3 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HepG2 cells using BCA3 antibody.