EMR1 Polyclonal Antibody
- Catalog No.:YT1544
- Applications:WB;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- EMR1
- Gene Name:
- EMR1
- Protein Name:
- EGF-like module-containing mucin-like hormone receptor-like 1
- Human Gene Id:
- 2015
- Human Swiss Prot No:
- Q14246
- Mouse Swiss Prot No:
- Q61549
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human EMR1. AA range:818-867
- Specificity:
- EMR1 Polyclonal Antibody detects endogenous levels of EMR1 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- EMR1;TM7LN3;EGF-like module-containing mucin-like hormone receptor-like 1;EGF-like module receptor 1;EMR1 hormone receptor
- Observed Band(KD):
- 98kD
- Background:
- This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
- Function:
- alternative products:Comment=Additional isoforms seem to exist,function:Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 6 EGF-like domains.,tissue specificity:Wide expression; increased levels in peripheral blood mononuclear cells.,
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein .
- Expression:
- Expression is restricted to eosinophils.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of Jurkat cells using EMR1 Polyclonal Antibody
- Western blot analysis of lysates from Jurkat cells, using EMR1 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HUVECcells using EMR1 antibody.