• Target：
• GALK1

• Fields：
• >>Galactose metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of nucleotide sugars

• Gene Name：
• GALK1

• Protein Name：
• Galactokinase

• Human Gene Id：
• 2584

• Human Swiss Prot No：
• P51570

• Mouse Swiss Prot No：
• Q9R0N0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GALK1. AA range:1-50

• Specificity：
• GALK1 Polyclonal Antibody detects endogenous levels of GALK1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GALK1;GALK;Galactokinase;Galactose kinase

• Observed Band(KD)：
• 45kD

• Background：
• Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008],

• Function：
• catalytic activity:ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate.,disease:Defects in GALK1 are the cause of galactosemia II [MIM:230200]. It is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.,function:Major enzyme for galactose metabolism.,pathway:Carbohydrate metabolism; galactose metabolism.,similarity:Belongs to the GHMP kinase family.,similarity:Belongs to the GHMP kinase family. GalK subfamily.,

• Subcellular Location：
• cytoplasm,cytosol,membrane,extracellular exosome,

• Expression：
• Blood,Brain,Fetal brain cortex,Lung,

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