GBP3 Polyclonal Antibody
- Catalog No.:YT1868
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- GBP3
- Fields:
- >>NOD-like receptor signaling pathway
- Gene Name:
- GBP3
- Protein Name:
- Guanylate-binding protein 3
- Human Gene Id:
- 2635
- Human Swiss Prot No:
- Q9H0R5
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530
- Specificity:
- GBP3 Polyclonal Antibody detects endogenous levels of GBP3 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- GBP3;Guanylate-binding protein 3;GTP-binding protein 3;GBP-3;Guanine nucleotide-binding protein 3
- Observed Band(KD):
- 64kD
- Background:
- This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],
- Function:
- function:Binds GTP, GDP and GMP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Unlikely isoform. Aberrant splice sites.,similarity:Belongs to the GBP family.,
- Subcellular Location:
- Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
- Expression:
- Brain,Prostate,
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using GBP3 Polyclonal Antibody
- Western Blot analysis of COLO205 cells using GBP3 Polyclonal Antibody
- Western blot analysis of lysates from HT-29 and COLO cells, using GBP3 Antibody. The lane on the right is blocked with the synthesized peptide.
- Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1,primary Antibody was diluted at 1:200(4° overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200