GBP3 Polyclonal Antibody

    • Catalog No.:YT1868
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • GBP3
      • Fields:
      • >>NOD-like receptor signaling pathway
      • Gene Name:
      • GBP3
      • Protein Name:
      • Guanylate-binding protein 3
      • Human Gene Id:
      • 2635
      • Human Swiss Prot No:
      • Q9H0R5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530
      • Specificity:
      • GBP3 Polyclonal Antibody detects endogenous levels of GBP3 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GBP3;Guanylate-binding protein 3;GTP-binding protein 3;GBP-3;Guanine nucleotide-binding protein 3
      • Observed Band(KD):
      • 64kD
      • Background:
      • This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],
      • Function:
      • function:Binds GTP, GDP and GMP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Unlikely isoform. Aberrant splice sites.,similarity:Belongs to the GBP family.,
      • Subcellular Location:
      • Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
      • Expression:
      • Brain,Prostate,
      • Products Images
      • Western Blot analysis of various cells using GBP3 Polyclonal Antibody
      • Western Blot analysis of COLO205 cells using GBP3 Polyclonal Antibody
      • Western blot analysis of lysates from HT-29 and COLO cells, using GBP3 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1,primary Antibody was diluted at 1:200(4° overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200