IRX1 Polyclonal Antibody

    • Catalog No.:YT2412
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • IRX1
      • Gene Name:
      • IRX1
      • Protein Name:
      • Iroquois-class homeodomain protein IRX-1
      • Human Swiss Prot No:
      • P78414
      • Mouse Swiss Prot No:
      • P81068
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human IRX1. AA range:221-270
      • Specificity:
      • IRX1 Polyclonal Antibody detects endogenous levels of IRX1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • IRX1;IRXA1;Iroquois-class homeodomain protein IRX-1;Homeodomain protein IRXA1;Iroquois homeobox protein 1
      • Observed Band(KD):
      • 47kD
      • Background:
      • This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011],
      • Function:
      • similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Brain,Lung,
      • Products Images
      • Western blot analysis of lysates from LOVO cells, using IRX1 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).